Challenges faced in managing cervical cancer patients who present post-operatively with more advanced disease in LMICs: Case studies from Cameroon

• Published in: Gynecologic oncology reports Vol. 55; p. 101485
• Main Authors: Ngalla, Calvin, Didymus, Jaff, Manjuh, Florence, Nwufor, Marius, Nkfusai, Joseph, Elit, Laure, Fokom Domgue, Joel
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01-10-2024; Elsevier
• Subjects: Advanced disease; Cameroon; Cervical cancer; Chemotherapy; Diagnosis; Follow-up; LMICs; Outcomes; Pathology; Radiotherapy; Surgery; Treatment; Advanced disease; Pathology; Chemotherapy; Cameroon; Treatment; Surgery; Diagnosis; LMICs; Radiotherapy; Cervical cancer; Outcomes; Follow-up
• ISSN: 2352-5789; 2352-5789
• DOI: 10.1016/j.gore.2024.101485

•Cervical cancer is the deadliest and the second most common cancer among women in Cameroon.•Most cases are diagnosed at an advanced stage and do not receive qualitycare.•Pathology services, diagnostic imaging procedures and modern treatment facilities for cervical cancer are lacking in this LMIC.•Provider’s collaboration, skills, and knowledge about this cancer should be improved.•Community education to enhance public awareness and patient navigation is needed.
Cameroon is a low-and-middle income country (LMIC) with one of the highest incidence and mortality from cervical cancer in Africa. In this Central African country where the prevalence of human immunodeficiency virus (HIV) is high and the screening coverage is low, cervical cancer is the most deadly and the second most common cancer among women. Notwithstanding the growing burden of cervical cancer in Cameroon, most patients - often of lower socioeconomic status - continue to encounter multi-level barriers to timely and adequate care. These include the lack of physical and financial access to healthcare facilities, limited quality pathology, imaging and treatment services, ignorance of disease by the population, shortage of a well-trained oncology workfroce, which result in significant delays in gaining access to screening, diagnosis, treatment and care. This paper presents 3 cases of patients with advanced cervical cancer who had surgery (hysterectomy) as primary treatment, without appropriate post-surgical investigation to further specify disease stage, persistence of residual disease, and need for adjuvant chemoradiation. Pathology services and diagnostic imaging procedures remain scarce and underused in LMIC countries like Cameroon. Healthcare professionals involved in patient care lack adequate knowledge, skills and collaborative strategy to properly navigate these patients. To address these challenges, the health system should be reinforced with adequate infrastructures, sustainable funding should be secured to enhance universal health coverage and promote cancer prevention and control programs, multidisciplinary teams and coordination of care among providers should be improved, and relevant health indicators should be put in place to better monitor the quality of care delivered to patients who are mostly vulnerable and uninformed.