Role of oxidative stress in PKC-delta upregulation and cardioprotection induced by chronic intermittent hypoxia

The aim was to determine whether increased oxidative stress during the adaptation to chronic intermittent hypoxia (CIH) plays a role in the induction of improved cardiac ischemic tolerance. Adult male Wistar rats were exposed to CIH in a hypobaric chamber (7,000 m, 8 h/day, 5 days/wk, 24-30 exposure...

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Bibliographic Details

Published in:	American journal of physiology. Heart and circulatory physiology Vol. 292; no. 1; p. H224
Main Authors:	Kolár, Frantisek, Jezková, Jana, Balková, Patricie, Breh, Jirí, Neckár, Jan, Novák, Frantisek, Nováková, Olga, Tomásová, Helena, Srbová, Martina, Ost'ádal, Bohuslav, Wilhelm, Jirí, Herget, Jan
Format:	Journal Article
Language:	English
Published:	United States 01-01-2007
Subjects:	Animals Chronic Disease Hypoxia - complications Hypoxia - physiopathology Hypoxia - prevention & control Ischemic Preconditioning, Myocardial - methods Male Myocardial Infarction - physiopathology Myocardial Infarction - prevention & control Oxidative Stress Protein Kinase C-delta - metabolism Rats Rats, Wistar Secondary Prevention Up-Regulation
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