Comparative analysis of SNP in estrogen-metabolizing enzymes for ovarian, endometrial, and breast cancers in Novosibirsk, Russia

We estimated the frequency of CYP1A1, CYP1A2, CYP1B1, CYP19, and SULT1A1 allelic variants in a female population of the Novosibirsk district and their association with the elevated risk of breast (BC), ovarian (OC), and endometrial (EC) cancers. Significant differences (OR = 2.34, p = 0.0002) in the...

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Bibliographic Details
Published in:	Advances in experimental medicine and biology Vol. 617; p. 359
Main Authors:	Gulyaeva, Lyudmila F, Mikhailova, Olga N, PustyInyak, Vladimir O, Kim, 4th, Inessa V, Gerasimov, Alexei V, Krasilnikov, Sergey E, Filipenko, Maxim L, Pechkovsky, Eugene V
Format:	Journal Article
Language:	English
Published:	United States 2008
Subjects:	Aromatase - genetics Aryl Hydrocarbon Hydroxylases Arylsulfotransferase - genetics Breast Neoplasms - enzymology Breast Neoplasms - genetics Breast Neoplasms - pathology Case-Control Studies Cytochrome P-450 CYP1A1 - genetics Cytochrome P-450 CYP1A2 - genetics Cytochrome P-450 CYP1B1 Cytochrome P-450 Enzyme System - genetics Endometrial Neoplasms - enzymology Endometrial Neoplasms - genetics Endometrial Neoplasms - pathology Estrogens - metabolism Female Genotype Humans Middle Aged Ovarian Neoplasms - enzymology Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Polymerase Chain Reaction Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide Russia Russia
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