α-Adducin nsSNPs affect mRNA secondary structure, protein modification and stability

Adducins help stabilize the spectrin-actin interactions along with other accessory cytoskeletal proteins. Adducins exist as a tetramer composed of either α/β or α/γ heterodimers. Polymorphisms in α-adducin (ADD1) gene have been shown to be associated with hypertension and erythrocyte deformability....

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Bibliographic Details

Published in:	Meta Gene Vol. 17; pp. 153 - 162
Main Author:	Goswami, Achintya Mohan
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01-09-2018
Subjects:	Alpha-adducin In silico mRNA nsSNP Pathogenicity Pathogenicity In silico mRNA Alpha-adducin nsSNP
Online Access:	Get full text
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