Lymph vessels, Na+ and the teleological science of hypertension

Lymph vessels, Na+ and the teleological science of hypertension

A recent study reports that adenosine A2A receptor-mediated lymphangiogenesis increases lymphatic clearance of excess Na + from the skin and reduces blood pressure, whereas impairment of this process leads to salt-sensitive hypertension. These findings raise intriguing physiological questions regard...

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Bibliographic Details
Published in:Nature reviews. Nephrology Vol. 19; no. 11; pp. 692 - 693
Main Author: Titze, Jens M.
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 01-11-2023
Nature Publishing Group
Subjects:
631/443/1338/243/785
631/443/319/1557
Adenosine
Blood pressure
Computer simulation
Diet
Hyperplasia
Hypertension
Hypotheses
Medicine
Medicine & Public Health
Nephrology
News & Views
news-and-views
Pharmacists
Physiology
Salt
Skin
Sodium
Vascular endothelial growth factor
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Summary:A recent study reports that adenosine A2A receptor-mediated lymphangiogenesis increases lymphatic clearance of excess Na + from the skin and reduces blood pressure, whereas impairment of this process leads to salt-sensitive hypertension. These findings raise intriguing physiological questions regarding the relationships among sodium, water and blood pressure.
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ISSN:1759-5061
1759-507X
DOI:10.1038/s41581-023-00770-5