Transplacental passage of a progesterone antagonist in monkeys

The progesterone antagonist RU 486 dramatically increases myometrial contractility of the pregnant uterus, making it a potential adjunctive therapy for labor induction or therapeutic pregnancy termination. Sixteen female cynomolgus monkeys were studied during the second or third trimester of pregnan...

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Bibliographic Details

Published in:	American journal of obstetrics and gynecology Vol. 159; no. 1; p. 238
Main Authors:	Wolf, J P, Chillik, C F, Itskovitz, J, Weyman, D, Anderson, T L, Ulmann, A, Baulieu, E E, Hodgen, G D
Format:	Journal Article
Language:	English
Published:	United States 01-07-1988
Subjects:	Animals Estrenes - pharmacokinetics Female Macaca fascicularis Maternal-Fetal Exchange - drug effects Mifepristone Placenta - metabolism Pregnancy Progestins - antagonists & inhibitors
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