Nebulized and intraperitoneal ketamine have equivalent antidepressant-like effect in the forced swim and tail suspension tests in mice

Major depressive disorder (MDD) is a debilitating illness that affects millions of people worldwide. Currently available antidepressants often take weeks to months to reach their full effect, which leads to an increased risk of suicidal behavior in patients with MMD. Intranasally, esketamine has eme...

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Bibliographic Details
Published in:	Pharmacology, biochemistry and behavior Vol. 233; p. 173674
Main Authors:	Brandão, Aida A C, Deus, Deborah L S, Duarte-Filho, Luiz A M S, Menezes, Pedro M N, Massaranduba, Ana B R, Silva, Fabrício S, Ribeiro, Luciano A A
Format:	Journal Article
Language:	English
Published:	United States 01-12-2023
Subjects:	Animals Antidepressive Agents - pharmacology Antidepressive Agents - therapeutic use Depression - drug therapy Depressive Disorder, Major - drug therapy Dexamethasone - therapeutic use Disease Models, Animal Hindlimb Suspension Humans Ketamine - pharmacology Ketamine - therapeutic use Mice Swimming Forced swimming test Antidepressant-like effects in mice Nebulized ketamine Tail suspension test
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