Toxicological study of the different organs of Corchorus olitorius L. plant with special reference to their cardiac glycosides content

• Published in: Zeitschrift für Ernährungswissenschaft Vol. 19; no. 1; p. 28
• Main Authors: Negm, S, El-Shabrawy, O, Arbid, M, Radwan, A S
• Format: Journal Article
• Language: English
• Published: Germany 01-03-1980
• Subjects: Animals; Blood Physiological Phenomena; Cardiac Glycosides - isolation & purification; Cardiac Glycosides - toxicity; Lethal Dose 50; Male; Mice; Plant Extracts - toxicity; Seeds - analysis; Tissue Distribution
• ISSN: 0044-264X
• DOI: 10.1007/BF02021069

The acute toxicity of the alcoholic extracts of seeds, roots stems and leaves of the fully mature Corchorus olitorius L. plant was determined in mice by intraperitoneal injection. The cardiac glycosides content of each extract was estimated and the correlation between the two investigated parameters was established. The chronic toxicity of the alcoholic extract of the seeds was determined in term of its haematological and symptomatical effects on mice upon intraperitoneal injection for a period of two months.