Burn Injury with Infection Alters Prostaglandin E2 Synthesis and Metabolism

OBJECTIVE:The aim of this study was to examine the relationship between prostaglandin synthesis and prostaglandin degradation in a model of burn injury with infection. METHODS:Male B2D6F1 mice were assigned to control, burn (16% dorsal scald burn), or burn with infection (burn with topical applicati...

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Bibliographic Details
Published in:	The Journal of Trauma: Injury, Infection, and Critical Care Vol. 47; no. 6; p. 1052
Main Authors:	Hahn, Elisabeth L., Tai, Hsin-Hsiung, He, Like K., Gamelli, Richard L.
Format:	Journal Article Conference Proceeding
Language:	English
Published:	Baltimore, MD Lippincott Williams & Wilkins, Inc 01-12-1999 Lippincott Williams & Wilkins
Subjects:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Blotting, Northern Blotting, Western Burns - complications Cyclooxygenase 2 Dinoprostone - biosynthesis Dinoprostone - metabolism Disease Models, Animal Emergency and intensive care: burns Gene Expression Regulation, Enzymologic - genetics Hydroxyprostaglandin Dehydrogenases - analysis Hydroxyprostaglandin Dehydrogenases - genetics Intensive care medicine Isoenzymes - analysis Isoenzymes - genetics Lung - chemistry Male Medical sciences Mice Mice, Inbred Strains Prostaglandin-Endoperoxide Synthases - analysis Prostaglandin-Endoperoxide Synthases - genetics Pseudomonas Infections - etiology Pseudomonas Infections - metabolism Pseudomonas Infections - pathology Rabbits Random Allocation RNA, Messenger - analysis Transcription, Genetic - genetics Wound Infection - etiology Wound Infection - metabolism Wound Infection - pathology Pseudomonadales Pathophysiology Rodentia Alteration Prostaglandin E2 Metabolism Trauma Infection Burn Sepsis syndrome Vertebrata Mammalia Synthesis Mouse Animal Bacteriosis Bacteria Pseudomonadaceae Pseudomonas aeruginosa
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