A Graph Grammar for Modelling RNA Folding

We propose a new approach for modelling the process of RNA folding as a graph transformation guided by the global value of free energy. Since the folding process evolves towards a configuration in which the free energy is minimal, the global behaviour resembles the one of a self-adaptive system. Eac...

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Bibliographic Details
Published in:Electronic proceedings in theoretical computer science Vol. 231; no. Proc. GaM 2016; pp. 31 - 41
Main Authors: Mamuye, Adane Letta, Merelli, Emanuela, Tesei, Luca
Format: Journal Article
Language:English
Published: Open Publishing Association 04-12-2016
Online Access:Get full text
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Summary:We propose a new approach for modelling the process of RNA folding as a graph transformation guided by the global value of free energy. Since the folding process evolves towards a configuration in which the free energy is minimal, the global behaviour resembles the one of a self-adaptive system. Each RNA configuration is a graph and the evolution of configurations is constrained by precise rules that can be described by a graph grammar.
ISSN:2075-2180
2075-2180
DOI:10.4204/EPTCS.231.3