Preliminary report: extracorporeal lung support for neonatal acute respiratory failure

• Published in: The Lancet (British edition) Vol. 335; no. 8702; p. 1364
• Main Authors: Chevalier, J Y, Durandy, Y, Batisse, A, Mathe, J C, Costil, J
• Format: Journal Article
• Language: English
• Published: England 09-06-1990
• Subjects: Acute Disease; Carbon Dioxide - blood; Extracorporeal Membrane Oxygenation - adverse effects; Extracorporeal Membrane Oxygenation - instrumentation; Extracorporeal Membrane Oxygenation - methods; Humans; Infant, Newborn; Infant, Premature, Diseases - therapy; Positive-Pressure Respiration - instrumentation; Positive-Pressure Respiration - methods; Respiratory Insufficiency - therapy; Time Factors
• ISSN: 0140-6736
• DOI: 10.1016/0140-6736(90)91244-5

A technique for ventilatory support of life-threatening neonatal acute respiratory failure by use of apnoeic oxygenation and low-frequency positive-pressure ventilation, with extracorporeal membrane CO2 removal through a single-cannula perfusion circuit, is described. 20 severely ill babies with respiratory failure were treated with this technique, 17 of whom survived with no clinical evidence of pulmonary handicap or neurological deficit at discharge from hospital. All 10 patients followed up at 6 months showed normal growth and development.