A Renal Clearable Nano‐Assembly with Förster Resonance Energy Transfer Amplified Superoxide Radical and Heat Generation to Overcome Hypoxia Resistance in Phototherapeutics

Given that type I photosensitizers (PSs) possess a good hypoxic tolerance, developing an innovative tactic to construct type I PSs is crucially important, but remains a challenge. Herein, we present a smart molecular design strategy based on the Förster resonance energy transfer (FRET) mechanism to...

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Bibliographic Details
Published in:	Angewandte Chemie International Edition Vol. 63; no. 44; pp. e202411514 - n/a
Main Authors:	Zhao, Yuan‐Yuan, Zhang, Xiaojun, Xu, Yihui, Chen, Zixuan, Hwang, Bokyeong, Kim, Heejeong, Liu, Hao, Li, Xingshu, Yoon, Juyoung
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 24-10-2024
Edition:	International ed. in English
Subjects:	Animals Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Cancer therapies Energy transfer Fluorescence Resonance Energy Transfer Förster resonance energy transfer Heat generation Hot Temperature Humans Hypoxia I.R. radiation Infrared Rays Irradiation Kidney - drug effects Kidney - metabolism Light irradiation Mice nanostructure Nanostructures - chemistry Photochemotherapy Photodynamic therapy Photosensitizing Agents - chemistry Photosensitizing Agents - pharmacology renal clearable Resonance Superoxide Superoxides - chemistry Superoxides - metabolism Tumors type I photoreaction Förster resonance energy transfer nanostructure renal clearable photodynamic therapy type I photoreaction
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