Manifestation and management of intravenous leiomyomatosis: A systematic review of the literature

Intravenous leiomyomatosis (IVL) is characterized by the presence of vascular extension and invasion of benign smooth muscle lesions in a worm-like manner from uterine fibroids into the systemic vasculature system. Surgery with complete tumour resection remains the main treatment approach, however b...

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Bibliographic Details
Published in:	Surgical oncology Vol. 45; p. 101879
Main Authors:	Lim, Wei How, Lamaro, Vincent P., Sivagnanam, Vasukhi
Format:	Journal Article
Language:	English
Published:	Oxford Elsevier Ltd 01-12-2022 Elsevier Limited
Subjects:	Cardiac tumours Case reports Fibroids Heart failure Heart surgery Hysterectomy Intravenous administration Literature reviews Morbidity Mortality Muscles Oophorectomy Pathology Patients Sarcoma Smooth muscle Software Surgical oncology Surgical outcomes Systematic review Tumors Uterine cancer Uterine tumours Uterus Vascular tumours Vein & artery diseases Uterine tumours Cardiac tumours Vascular tumours Surgical oncology
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Summary:	Intravenous leiomyomatosis (IVL) is characterized by the presence of vascular extension and invasion of benign smooth muscle lesions in a worm-like manner from uterine fibroids into the systemic vasculature system. Surgery with complete tumour resection remains the main treatment approach, however both treated and untreated of this disease is associated with high morbidity and mortality. The aim of this systematic review is to highlight the systemic manifestations and surgical management of IVL.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Undefined-4
ISSN:	0960-7404 1879-3320
DOI:	10.1016/j.suronc.2022.101879