A case report of a mucormycosis caused by Lichtheimia ramosa in a patient with acute myeloid leukemia

Mucormycosis because of Lichtheimia ramosa is an unusual opportunistic fungal infection that can potentially be fatal in immunocompromised hosts. We present a fatal case of mucormycosis, affecting a 59-year-old woman with diabetes and acute myeloid leukemia. Palatal mucormycosis with sinonasal invas...

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Bibliographic Details
Published in:	Reviews in medical microbiology Vol. 33; no. 1; pp. e4 - e9
Main Authors:	Houaida, Trabelsi, Sourour, Neji, Ines, Hadrich, Imen, Frikha, Moez, Mdhaffar, Nahed, Khemakhem, Hayet, Sellami, Fattouma, Makni, Moez, Elloumi, Ali, Ayadi
Format:	Journal Article
Language:	English
Published:	Lippincott Williams & Wilkins 01-01-2022
Online Access:	Get full text
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Summary:	Mucormycosis because of Lichtheimia ramosa is an unusual opportunistic fungal infection that can potentially be fatal in immunocompromised hosts. We present a fatal case of mucormycosis, affecting a 59-year-old woman with diabetes and acute myeloid leukemia. Palatal mucormycosis with sinonasal invasion was confirmed by mycological culture and histopathology. Exact species identification of Lichtheimia ramosa was performed by PCR-sequencing of ITS1-5.8S- ITS2 regions of the ribosomal genes. The patient was managed medically as surgical approach was not possible, and she unfortunately died. To our knowledge, this is the first report of Lichtheimia ramosa infection in Tunisia confirmed molecularly.
ISSN:	0954-139X
DOI:	10.1097/MRM.0000000000000299