Neonatal outcome following exposure to organophosphorous pesticides

• Published in: Archives of biological sciences Vol. 62; no. 1; pp. 1 - 8
• Main Authors: Djordjevic, M., Vujic, Ana, Jovanovic, B., Djordjevic, Gordana, Sazdanovic, Maja, Sazdanovic, P.
• Format: Journal Article
• Language: English
• Published: University of Belgrade, University of Novi Sad 2010
• Subjects: CNS disorders; newborn morbidity; Organophosphorous pesticides
• DOI: 10.2298/ABS1001001D
• EISSN: 1821-4339
• ISSN: 0354-4664

The aim of our study was to determine the neonatal outcome in mothers and children exposed to organophosphorous pesticides (OP). We found that 22.4% pregnant women were exposed to organophosphorous pesticides. OP pesticide concentration was higher in breast milk, newborn sera than maternal sera. Newborn parameters such as birth weight, birth length, head circumference, Apgar score and presence of meconium, as well as gestational age of delivery, showed no significant difference between the two groups. However, postpartum weight loss, hospitalization duration, levels of newborn bilirubin and glycaemia differed significantly between the two groups. Morbidity and presence of CNS disorders were six times and more than twelve times higher, respectively, in the OP-exposed than in the OP pesticide non-exposed group.
Cilj ove studije je da odredi uticaj organo-fosfornih pesticida (OP) na trudnice i novorodjencad nakon registrovanog niskog dejstva. Registrovali smo pojavu u 22,4% slucajeva ekspozicije trudnica i novorodjencadi. Koncentracija organofosfornih pesticida je bila visa u majcinom mleku, serumu novorodjencadi nego majcinskom serumu. Parametri novorodjencadi kao sto su tezina, duzina, obim glave, Apgar skor i prisustvo mekonijuma u plodovoj vodi u toku porodjaja nisu pokazivali razlike izmedju dve grupa. S druge strane, postporodjajni gubitak mase, duzina hospitalizacije, serumski nivoi glikemije, bilirubina su se znacajno razlikovali medju grupama. Morbiditet i bolesti CNS su bile sest i vise od dvanaest puta vise u organofosforno izlozenoj nego u neizlozenoj grupi trudnica i novorodjencadi.