Recent progress in catalytic acyloxylation of C(sp3)‐H bonds

• Published in: Applied organometallic chemistry Vol. 36; no. 3
• Main Authors: Antonov, Artem A., Bryliakov, Konstantin P.
• Format: Journal Article
• Language: English
• Published: Chichester Wiley Subscription Services, Inc 01-03-2022
• Subjects: Acetals; acetoxylation; acyloxylation; Additives; Alkenes; Amides; Amines; Carbonyl compounds; Carbonyls; Carboxylic acids; Chemistry; C‐H bond activation; mechanism; oxidation; Oxidizing agents; Oximes; Substrates; Transition metals
• ISSN: 0268-2605; 1099-0739
• DOI: 10.1002/aoc.6499

Herewith, recent progress in the transition metal catalyzed, as well as metal‐free and electrochemical selective acyloxylations of C(sp3)‐H bonds is surveyed. The corresponding modifications of different substrate types such as amines, amides, oximes, aminoacids, nitrogen‐containing heterocycles, olefins, carbonyl compounds, carboxylic acids, and acetals are covered, focusing on their synthetic potential. Correlations between the nature of the catalyst, oxidant, additives, conditions, and the acyloxylation regio‐ and chemoselectivity, are revealed, and available mechanistic details are discussed briefly. The time span of the review is 2015 to present time.
Recent progress in the transition metal catalyzed, as well as metal‐free and electrochemical selective acyloxylations of C(sp3)‐H bonds of organic molecules, is surveyed, focusing on the synthetic potential of the considered approaches. Correlations between the nature of the catalyst, oxidant, additives, conditions, and the acyloxylation regio‐ and chemoselectivity, as well as available mechanistic details, are discussed. The time span of the review is 2015 to present time.