Predicting In Vivo Target Occupancy (TO) Profiles via Physiologically Based Pharmacokinetic–TO Modeling of Warfarin Pharmacokinetics in Blood: Importance of Low Dose Data and Prediction of Stereoselective Target Interactions

Predicting In Vivo Target Occupancy (TO) Profiles via Physiologically Based Pharmacokinetic–TO Modeling of Warfarin Pharmacokinetics in Blood: Importance of Low Dose Data and Prediction of Stereoselective Target Interactions

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Bibliographic Details
Published in:Drug metabolism and disposition Vol. 51; no. 9; pp. 1145 - 1156
Main Authors: Lee, Wooin, Kim, Min-Soo, Kim, Jiyoung, Aoki, Yasunori, Sugiyama, Yuichi
Format: Journal Article
Language:English
Published: 01-09-2023
Online Access:Get full text
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Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:0090-9556
1521-009X
DOI:10.1124/dmd.122.000968