Results of a double-blind placebo-controlled study of the double-stranded RNA drug polyI:polyC12U in the treatment of HIV infection

In this multicenter, randomized, double-blind study the activity of polyI:polyC12U administered with zidovudine was evaluated in the treatment of HIV infection. Thirty-six HIV-positive, pre-AIDS individuals (100-500 CD4+ cells/mm3) who had had at least six months of zidovudine therapy received polyI...

Full description

Saved in:

Bibliographic Details
Published in:	European journal of clinical microbiology & infectious diseases Vol. 15; no. 7; pp. 580 - 587
Main Authors:	THOMPSON, K. A, STRAYER, D. R, SALVATO, P. D, THOMPSON, C. E, KLIMAS, N, MOLAVI, A, HAMILL, A. K, ZHENG, Z, VENTURA, D, CARTER, W. A
Format:	Journal Article
Language:	English
Published:	Berlin Springer 01-07-1996
Subjects:	Acquired Immunodeficiency Syndrome - etiology Adult Anti-HIV Agents - adverse effects Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Antiviral Agents - adverse effects Antiviral Agents - therapeutic use Biological and medical sciences Candida albicans - immunology CD4 Lymphocyte Count Cross-Over Studies Disease Progression Double-Blind Method Drug Hypersensitivity Drug Therapy, Combination Female HIV Core Protein p24 - analysis HIV Infections - drug therapy Humans Hypersensitivity, Delayed Male Medical sciences Middle Aged Mumps - immunology Pharmacology. Drug treatments Poly I-C - adverse effects Poly I-C - therapeutic use Poly U - adverse effects Poly U - therapeutic use RNA, Double-Stranded Skin Tests Tetanus - immunology Trichophyton - immunology Zidovudine - adverse effects Zidovudine - therapeutic use Infection Human Immunopathology Chemotherapy Double stranded RNA Treatment Viral disease Treatment efficiency Double blind study AIDS Immune deficiency
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!