The benefits of ashwagandha ( Withania somnifera ) supplements on brain function and sports performance

• Published in: Frontiers in nutrition (Lausanne) Vol. 11; p. 1439294
• Main Authors: Guo, Shiyi, Rezaei, Mohammad J
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 02-08-2024
• Subjects: antioxidant response; ashwagandha; brain function; exercise; inflammation; sports performance; ashwagandha; exercise; brain function; inflammation; antioxidant response; sports performance
• ISSN: 2296-861X; 2296-861X
• DOI: 10.3389/fnut.2024.1439294

Ashwagandha or Withania somnifera is an herbal plant belonging to the Solanaceae family. Because of its wide range of phytochemicals, ashwagandha root extract has been used in numerous research studies, either alone or in conjunction with other natural plants, for various biomedical applications, which include its anti-microbial, anti-inflammatory, anti-stress, anti-tumor, cardioprotective, and neuroprotective properties. Additionally, it improves endothelial function, lowers reactive oxygen species, controls apoptosis, and improves mitochondrial function. These properties make it a useful treatment for a variety of conditions, including age-related symptoms, anxiety, neurodegenerative diseases, diabetes, stress, arthritis, fatigue, and cognitive/memory impairment. Despite the numerous benefits of ashwagandha supplementation, there have been just four meta-analyses on the herb's effectiveness in treating anxiety, neurobehavioral disorders, impotence, and infertility. Moreover, no reviews exist that examine how ashwagandha affects antioxidant response and physical sports performance. Consequently, the goal of this study was to analyze the scientific literature regarding the effects of ashwagandha consumption on antioxidant response and athletic performance.