The Demonstration of Subtype (D or Y)-Specific Determinants on the Surface of the Presumed Hepatitis B Virus

Dane particles isolated from the sera of HBsAg/ad and HBsAg/ay carriers were reacted with monospecific antibodies to the d and y subtype-specific determinants of HBsAg/. Dane particles from HBsAg/ad expressed the d determinant on their surfaces and those from HBsAg/ay sera contained the y specificit...

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Bibliographic Details
Published in:The Journal of immunology (1950) Vol. 119; no. 4; pp. 1542 - 1544
Main Authors: Hess, G, Shih, J. W-K, Kaplan, P. M, Gerin, J. L
Format: Journal Article
Language:English
Published: United States Am Assoc Immnol 01-10-1977
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Summary:Dane particles isolated from the sera of HBsAg/ad and HBsAg/ay carriers were reacted with monospecific antibodies to the d and y subtype-specific determinants of HBsAg/. Dane particles from HBsAg/ad expressed the d determinant on their surfaces and those from HBsAg/ay sera contained the y specificity. Both complete (DNA-P and HBcAg) and defective (HBcAg alone) Dane particles expressed the subtype-specific determinants.
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ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.119.4.1542