Functional genomics of apocarotenoids in saffron: insights from chemistry, molecular biology and therapeutic applications

Saffron is considered to be the costliest spice of the world. It has been regarded as highly valued medicinal plant in Ayurveda to treat various ailments. Over the past few years, considerable interest has developed in saffron because of its anticancer, antimutagenic, antioxidant and immunomodulator...

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Published in:Briefings in functional genomics Vol. 16; no. 6; pp. 336 - 347
Main Authors: Dhar, Manoj K, Sharma, Munish, Bhat, Archana, Chrungoo, Nikhil K, Kaul, Sanjana
Format: Journal Article
Language:English
Published: England 01-11-2017
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Abstract Saffron is considered to be the costliest spice of the world. It has been regarded as highly valued medicinal plant in Ayurveda to treat various ailments. Over the past few years, considerable interest has developed in saffron because of its anticancer, antimutagenic, antioxidant and immunomodulatory properties. Saffron's colour, bitter taste and aroma are its three main and peculiar characteristics, which are conferred by three chemicals namely: crocin, picrocrocin and safranal, respectively. The present review focuses on recent research/progress made in saffron in the area of functional genomics and highlights the potential of several genes and transcription factors involved in carotenoid/apocarotenoid pathway and responsible for flavour and aroma of saffron.
AbstractList Saffron is considered to be the costliest spice of the world. It has been regarded as highly valued medicinal plant in Ayurveda to treat various ailments. Over the past few years, considerable interest has developed in saffron because of its anticancer, antimutagenic, antioxidant and immunomodulatory properties. Saffron's colour, bitter taste and aroma are its three main and peculiar characteristics, which are conferred by three chemicals namely: crocin, picrocrocin and safranal, respectively. The present review focuses on recent research/progress made in saffron in the area of functional genomics and highlights the potential of several genes and transcription factors involved in carotenoid/apocarotenoid pathway and responsible for flavour and aroma of saffron.
Author Dhar, Manoj K
Chrungoo, Nikhil K
Bhat, Archana
Sharma, Munish
Kaul, Sanjana
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Issue 6
Keywords genomics
apocarotenoid biosynthesis pathway
saffron
carotenoids
Crocus sativus
transcription factors
Language English
License The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.
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Snippet Saffron is considered to be the costliest spice of the world. It has been regarded as highly valued medicinal plant in Ayurveda to treat various ailments. Over...
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SubjectTerms Carotenoids - metabolism
Carotenoids - therapeutic use
Crocus - chemistry
Crocus - genetics
Gene Expression Regulation, Plant
Genes, Plant
Transcription, Genetic
Title Functional genomics of apocarotenoids in saffron: insights from chemistry, molecular biology and therapeutic applications
URI https://www.ncbi.nlm.nih.gov/pubmed/28369196
https://search.proquest.com/docview/1884164202
Volume 16
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