Pitfalls in Coagulation Testing

Assays in the coagulation laboratory are affected by numerous variables. Variables which have impact on the test result can lead to incorrect results, and potentially to consequences for further diagnostic and therapeutic decisions made by the clinician. The interferences can be separated into three...

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Bibliographic Details
Published in:Hamostaseologie Vol. 43; no. 1; p. 60
Main Author: Sachs, Ulrich J
Format: Journal Article
Language:English
Published: Germany 01-02-2023
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Summary:Assays in the coagulation laboratory are affected by numerous variables. Variables which have impact on the test result can lead to incorrect results, and potentially to consequences for further diagnostic and therapeutic decisions made by the clinician. The interferences can be separated into three main groups: interferences, with an actual impairment of the patient's coagulation system (congenital or acquired); interferences, which usually occur in the pre-analytical phase; and interferences, because of the presence of drugs (mainly anticoagulants) in the blood to be tested. This article discusses some of these interferences in seven instructive cases of (near) miss events as an approach to generate more attention to these issues.
ISSN:2567-5761
DOI:10.1055/a-1981-7939