Transforming growth factor-beta is generated in the course of hypersensitivity pneumonitis: contribution to collagen synthesis

Mice of the C57BL/6 strain were instilled with optimal doses (150 micrograms/day for 3 days/wk) of the thermophilic actinomycete Faeni rectivirgula (also known as Saccharopolyspora rectivirgula or Micropolyspora faeni) to induce a hypersensitivity pneumonitis inflammation that mimics the human disea...

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Bibliographic Details

Published in:	American journal of respiratory cell and molecular biology Vol. 7; no. 2; p. 156
Main Authors:	Denis, M, Ghadirian, E
Format:	Journal Article
Language:	English
Published:	United States 01-08-1992
Subjects:	Alveolitis, Extrinsic Allergic - immunology Alveolitis, Extrinsic Allergic - metabolism Animals Bronchoalveolar Lavage Fluid - cytology Collagen - biosynthesis Disease Models, Animal Fibroblasts - metabolism Lung - cytology Macrophages, Alveolar - metabolism Mice Mice, Inbred C57BL Saccharopolyspora - immunology Transforming Growth Factor beta - biosynthesis
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