Effects of semax on the activity of carboxypeptidase H in brain regions and adrenal glands of rats
We studied the effects of a single semax administration to rats on the activity of carboxypeptidase H, a basic carboxypeptidase involved in the final stage of formation of biologically active peptides from their precursors. We found that the drug induced a long-term increase in the activity of carbo...
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| Published in: | Neurochemical journal Vol. 5; no. 2; pp. 150 - 152 |
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| Format: | Journal Article |
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| Abstract | We studied the effects of a single semax administration to rats on the activity of carboxypeptidase H, a basic carboxypeptidase involved in the final stage of formation of biologically active peptides from their precursors. We found that the drug induced a long-term increase in the activity of carboxypeptidase, which lasted for 24 h. We believe that this change in the activity of the enzyme studied may serve as one of the factors that mediate semax action. |
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| AbstractList | We studied the effects of a single semax administration to rats on the activity of carboxypeptidase H, a basic carboxypeptidase involved in the final stage of formation of biologically active peptides from their precursors. We found that the drug induced a long-term increase in the activity of carboxypeptidase, which lasted for 24 h. We believe that this change in the activity of the enzyme studied may serve as one of the factors that mediate semax action. |
| Author | Gengin, M. T. Solov’ev, V. B. Zhivaeva, L. V. Latynova, I. V. Sollertinskaya, T. N. |
| Author_xml | – sequence: 1 givenname: V. B. surname: Solov’ev fullname: Solov’ev, V. B. email: solowew@rambler.ru organization: Penza State Pedagogical University – sequence: 2 givenname: M. T. surname: Gengin fullname: Gengin, M. T. organization: Penza State Pedagogical University – sequence: 3 givenname: T. N. surname: Sollertinskaya fullname: Sollertinskaya, T. N. organization: Sechenov Institute of Evolutionary Physiology and Biochemistry – sequence: 4 givenname: I. V. surname: Latynova fullname: Latynova, I. V. organization: Penza State Pedagogical University – sequence: 5 givenname: L. V. surname: Zhivaeva fullname: Zhivaeva, L. V. organization: Penza State Pedagogical University |
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| Keywords | neuropeptides brain carboxypeptidase H adrenal glands semax |
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| Title | Effects of semax on the activity of carboxypeptidase H in brain regions and adrenal glands of rats |
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