Effects of semax on the activity of carboxypeptidase H in brain regions and adrenal glands of rats

We studied the effects of a single semax administration to rats on the activity of carboxypeptidase H, a basic carboxypeptidase involved in the final stage of formation of biologically active peptides from their precursors. We found that the drug induced a long-term increase in the activity of carbo...

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Bibliographic Details
Published in:	Neurochemical journal Vol. 5; no. 2; pp. 150 - 152
Main Authors:	Solov’ev, V. B., Gengin, M. T., Sollertinskaya, T. N., Latynova, I. V., Zhivaeva, L. V.
Format:	Journal Article
Language:	English
Published:	Dordrecht SP MAIK Nauka/Interperiodica 01-06-2011
Subjects:	Biomedical and Life Sciences Biomedicine Neurosciences Short Communications neuropeptides brain carboxypeptidase H adrenal glands semax
Online Access:	Get full text
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Summary:	We studied the effects of a single semax administration to rats on the activity of carboxypeptidase H, a basic carboxypeptidase involved in the final stage of formation of biologically active peptides from their precursors. We found that the drug induced a long-term increase in the activity of carboxypeptidase, which lasted for 24 h. We believe that this change in the activity of the enzyme studied may serve as one of the factors that mediate semax action.
ISSN:	1819-7124 1819-7132
DOI:	10.1134/S1819712411020115