Giant congenital melanocytic nevus with neurofibroma-like lesions and onset of vitiligo

• Published in: Journal of Dermatology and Dermatologic Surgery Vol. 19; no. 1; pp. 58 - 61
• Main Authors: Iman Hadj, Mariam Meziane, Taoufik Harmouch, Fatima Zahra Mernissi
• Format: Journal Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 01-01-2015
• Subjects: Giant congenital melanocytic nevus; Melanoma; Neurofibromatosis; Neurotization; Vitiligo
• ISSN: 2352-2410
• DOI: 10.1016/j.jdds.2014.08.002

Giant congenital pigmented nevus and neurofibromatosis type 1 may rarely occur together. We reported here an unusual case where giant congenital melanocytic nevus was associated with neurofibroma-like lesions and vitiligo, emphasizing the clinical and histological diagnostic difficulties posed by this presentation, the signification of vitiligo which can testify of a possible malignant transformation of the giant nevus to a melanoma, and highlights the importance of an accurate diagnosis and a close follow-up of such patients.