Enhanced adrenal responsiveness to angiotensin II in patients with low renin essential hypertension

Enhanced adrenal responsiveness to angiotensin II in patients with low renin essential hypertension

The plasma aldosterone response to infused angiotensin II was determined in normal controls and in patients with normal renin and with low renin essential hypertension. The patients with low renin essential hypertension showed an enhanced plasma aldosterone response when compared to the other two gr...

Full description

Saved in:
Bibliographic Details
Published in:The journal of clinical endocrinology and metabolism Vol. 48; no. 2; p. 266
Main Authors: Marks, A D, Marks, D B, Kanefsky, T M, Adlin, V E, Channick, B J
Format: Journal Article
Language:English
Published: United States 01-02-1979
Subjects:
Adolescent
Adrenal Glands - physiopathology
Adult
Aldosterone - blood
Angiotensin II
Dose-Response Relationship, Drug
Humans
Hypertension - blood
Middle Aged
Potassium - blood
Renin - blood
Sodium - blood
Online Access:Get more information
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The plasma aldosterone response to infused angiotensin II was determined in normal controls and in patients with normal renin and with low renin essential hypertension. The patients with low renin essential hypertension showed an enhanced plasma aldosterone response when compared to the other two groups. This finding may explain why plasma aldosterone levels remain within normal limits in the face of suppressed plasma renin and angiotensin II concentrations in low renin essential hypertension.
ISSN:0021-972X
DOI:10.1210/jcem-48-2-266