Kinetic and mechanistic studies on reactions of diruthenium(II,III) with biologically relevant reducing agents

Diruthenium(ii,iii)-tetracarboxylates have shown promising anticancer properties as metallotherapeutics. On the basis of the role that bio-reducing agents may play on the mode of action of ruthenium-based anticancer drugs, we performed detailed kinetic studies on the reaction of ascorbic acid and gl...

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Bibliographic Details

Published in:	Dalton transactions : an international journal of inorganic chemistry Vol. 42; no. 48; p. 16796
Main Authors:	Santos, Rodrigo Luis Silva Ribeiro, van Eldik, Rudi, de Oliveira Silva, Denise
Format:	Journal Article
Language:	English
Published:	England 28-12-2013
Subjects:	Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Ascorbic Acid - metabolism Carboxylic Acids - chemistry Carboxylic Acids - pharmacology Glutathione - metabolism Kinetics Reducing Agents - metabolism Ruthenium - chemistry Ruthenium - pharmacology
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