Arachidonic acid elicits a substrate-gated proton current associated with the glutamate transporter EAAT4

Arachidonic acid modulates both electrical and biochemical properties of membrane proteins involved in cellular signaling. In Xenopus laevis oocytes expressing the excitatory amino acid transporter EAAT4, physiologically relevant concentrations of arachidonic acid increase the amplitude of the subst...

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Bibliographic Details
Published in:	Nature neuroscience Vol. 1; no. 2; pp. 105 - 113
Main Authors:	Amara, Susan G, Fairman, Wendy A, Sonders, Mark S, Murdoch, Geoffrey H
Format:	Journal Article
Language:	English
Published:	United States 01-06-1998
Subjects:	Amino Acid Transport System X-AG Animals Anions - metabolism Arachidonic Acid - pharmacology Biological Transport - physiology Electric Conductivity Female Glutamate Plasma Membrane Transport Proteins Ion Channel Gating - physiology Ion Channels - physiology Kinetics Oocytes Protons Receptors, Glutamate - physiology Substrate Specificity Symporters Xenopus
Online Access:	Get full text
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