Computerized cranial tomography in Wilson disease

Hepatolenticular degeneration (Wilson disease) is suspected by the clinical picture and confirmed by characteristic laboratory demonstration of impaired copper metabolism. Three patients with Wilson disease involving the basal ganglia were shown to have abnormalities on computerized tomography (CT)...

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Bibliographic Details
Published in:	Neurology Vol. 29; no. 6; p. 866
Main Authors:	Nelson, R F, Guzman, D A, Grahovac, Z, Howse, D C
Format:	Journal Article
Language:	English
Published:	United States 01-06-1979
Subjects:	Adult Basal Ganglia - diagnostic imaging Ceruloplasmin - analysis Female Hepatolenticular Degeneration - diagnostic imaging Hepatolenticular Degeneration - drug therapy Humans Male Neurocognitive Disorders - diagnosis Penicillamine - therapeutic use Tomography, X-Ray Computed
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Summary:	Hepatolenticular degeneration (Wilson disease) is suspected by the clinical picture and confirmed by characteristic laboratory demonstration of impaired copper metabolism. Three patients with Wilson disease involving the basal ganglia were shown to have abnormalities on computerized tomography (CT) scan, whereas four other patients without signs of cerebral involvement had normal brain scans. Wilson disease may be added to the long list of diseases to which the EMI scan may make a useful diagnostic contribution.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0028-3878 1526-632X
DOI:	10.1212/WNL.29.6.866