Simple and Acid-Free Hydrothermal Synthesis of Bioactive Glass 58SiO2-33CaO-9P2O5 (wt%)

• Published in: Crystals (Basel) Vol. 11; no. 3; p. 283
• Main Authors: Anh Tuan, Ta, V. Guseva, Elena, Anh Tien, Nguyen, Tan Dat, Ho, Vuong, Bui Xuan
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01-03-2021
• Subjects: acid-free hydrothermal; Acids; Adsorption; bioactive glass; bioactivity; Biocompatibility; Bioglass; Biological activity; Biomedical materials; Body fluids; cell viability; Emission analysis; Fibroblasts; hydroxyapatite; In vitro methods and tests; Inductively coupled plasma; Morphology; Nitrates; Optical emission spectroscopy; Phase composition; Pore size; Sintering; Sol-gel processes; Stainless steel; Synthesis; Thermal analysis; Thermodynamic properties; United States > US
• ISSN: 2073-4352; 2073-4352
• DOI: 10.3390/cryst11030283

The paper focuses on the acid-free hydrothermal process for the synthesis of bioactive glass. The new method avoids the use of harmful acid catalysts, which are usually used in the sol-gel process. On the other hand, the processing time was reduced compared with the sol-gel method. A well-known ternary bioactive glass 58SiO2-33CaO-9P2O5 (wt%), which has been widely synthesized through the sol-gel method, was selected to apply to this new process. Thermal behavior, textural property, phase composition, morphology, and ionic exchange were investigated by thermal analysis, N2 adsorption/desorption, XRD, FTIR, SEM, and inductively coupled plasma optical emission spectrometry (ICP-OES) analysis. The bioactivity and biocompatibility of synthetic bioactive glass were evaluated by in vitro experiments with a simulated body fluid (SBF) solution and cell culture medium. The obtained results confirmed that the acid-free hydrothermal process is one of the ideal methods for preparing ternary bioactive glass.