Evaluation of a new Seralyzer assay for carbamazepine

The performance of a new dry-phase, strip immunoassay technique for the analysis of serum carbamazepine concentrations (Seralyzer), was compared to a standard high performance liquid chromatography (HPLC) method. One hundred blood samples were collected from 87 patients and analysed using both techn...

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Bibliographic Details
Published in:	Therapeutic drug monitoring Vol. 10; no. 3; p. 355
Main Authors:	McGovern, E M, MacRobbie, A, Thomson, A H, Whiting, B
Format:	Journal Article
Language:	English
Published:	United States 01-01-1988
Subjects:	Carbamazepine - blood Chromatography, High Pressure Liquid Evaluation Studies as Topic Female Humans Immunoassay - methods Male Reagent Strips
Online Access:	Get more information
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Summary:	The performance of a new dry-phase, strip immunoassay technique for the analysis of serum carbamazepine concentrations (Seralyzer), was compared to a standard high performance liquid chromatography (HPLC) method. One hundred blood samples were collected from 87 patients and analysed using both techniques. There was no significant difference between the concentrations measured by either technique, and the results were highly correlated (r = 0.97). The Seralyzer is a rapid and accurate method for use in carbamazepine therapeutic drug monitoring.
ISSN:	0163-4356
DOI:	10.1097/00007691-198803000-00022