A Facile Synthesis of New 3-Substituted-2,3- dihydropyrido[3,2-d]pyrimidine-2,4-diones

A Facile Synthesis of New 3-Substituted-2,3- dihydropyrido[3,2-d]pyrimidine-2,4-diones

Pyrido[3,2-d]pyrimidine-2,4-diones derivatives have been synthesized in good yields by two efficient synthetic routes, the first one through an hetero-cyclization on the ureas derivatives 3a-e under alkaline conditions, the second one by condensation of the isocyanate 2 with various arylalkylamines...

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Bibliographic Details
Published in:Synthetic communications Vol. 33; no. 24; pp. 4259 - 4268
Main Authors: Mamouni, R., Akssira, M., Aadil, M., Elhakmaoui, A., Lasri, J., Zaballos-Garcia, E.
Format: Journal Article
Language:English
Published: Taylor & Francis Group 31-12-2003
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Summary:Pyrido[3,2-d]pyrimidine-2,4-diones derivatives have been synthesized in good yields by two efficient synthetic routes, the first one through an hetero-cyclization on the ureas derivatives 3a-e under alkaline conditions, the second one by condensation of the isocyanate 2 with various arylalkylamines in pyridine.
ISSN:0039-7911
1532-2432
DOI:10.1081/SCC-120026855