Peripherally restricted PICK1 inhibitor mPD5 ameliorates pain behaviors in murine inflammatory and neuropathic pain models

Chronic pain is a complex, debilitating, and escalating health problem worldwide, impacting one in five adults. Current treatment is compromised by dose-limiting side effects including high abuse liability, loss of ability to function socially and professionally, fatigue, drowsiness, and apathy. PIC...

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Bibliographic Details

Published in:	JCI insight Vol. 9; no. 20
Main Authors:	Jensen, Kathrine Louise, Christensen, Nikolaj Riis, Goddard, Carolyn Marie, Jager, Sara Elgaard, Noes-Holt, Gith, Kanneworff, Ida Buur, Jakobsen, Alexander, Jiménez-Fernández, Lucía, Peck, Emily G, Sivertsen, Line, Comaposada-Baro, Raquel, Houser, Grace Anne, Mayer, Felix Paul, Diaz-delCastillo, Marta, Topp, Marie Løth, Hopkins, Chelsea, Thomsen, Cecilie Dubgaard, Ibrahim Soltan, Ahmed Barakat, Tidenmand, Federik Grønbæk, Arleth, Lise, Heegaard, Anne-Marie, Sørensen, Andreas Toft, Madsen, Kenneth Lindegaard
Format:	Journal Article
Language:	English
Published:	United States American Society for Clinical Investigation 17-09-2024
Subjects:	Neuroscience Pharmacology Pain Peptides
Online Access:	Get full text
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