Concept of extremes in vascular aging: from early vascular aging to supernormal vascular aging

[Excerpt] With advancing age, changes in the arterial wall contribute to what has been called vascular aging, and in some prematurely affected subjects even early vascular aging (EVA).1–5 Several years ago,1 we listed various components of EVA, including arteriosclerosis, atherosclerosis, and excess...

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Bibliographic Details
Published in:	Hypertension (Dallas, Tex. 1979) Vol. 74; no. 2; pp. 218 - 288
Main Authors:	Laurent, Stephane, Boutouyrie, Pierre, Cunha, Pedro Miguel Guimarães Marques, Lacolley, Patrick, Nilsson, Peter M.
Format:	Journal Article
Language:	English
Published:	American Heart Association 01-08-2019 American Heart Association, Inc
Subjects:	Science & Technology
Online Access:	Get full text
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Summary:	[Excerpt] With advancing age, changes in the arterial wall contribute to what has been called vascular aging, and in some prematurely affected subjects even early vascular aging (EVA).1–5 Several years ago,1 we listed various components of EVA, including arteriosclerosis, atherosclerosis, and excess vasoconstriction, with their clinical expression: arterial stiffening and increased central pulse pressure, carotid intima media thickening and endothelial dysfunction, and increased total peripheral resistance, respectively.[...] This review was funded by INSERM, Paris Descartes University; Lund University, the Swedish Research Council; and the Minho University
ISSN:	0194-911X 1524-4563
DOI:	10.1161/HYPERTENSIONAHA.119.12655