Role of NK cells and adaptive immunity in “immunoediting”: Recent developments

Role of NK cells and adaptive immunity in “immunoediting”: Recent developments

Abstract The role of the different arms of the Immune System in the control and elimination of tumors has been the subject of increasing interest in recent years. Here, some recent findings adding support to the role of NK cells in the elimination of spontaneous tumors in transgenic models of tumori...

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Bibliographic Details
Published in:Inmunología (1987) Vol. 27; no. 3; pp. 141 - 146
Main Author: Seren Bernardone, I
Format: Journal Article
Language:English
Published: Elsevier España 01-07-2008
Subjects:
Allergy and Immunology
Células NK
Immune surveillance
Immunoediting
Inmunidad Tumoral
Inmunoedición
Linfocitos T
NK cells
T lymphocytes
Tumor immunity
Vigilancia inmunológica
T lymphocytes
Inmunoedición
Linfocitos T
NK cells
Tumor immunity
Immunoediting
Inmunidad Tumoral
Immune surveillance
Vigilancia inmunológica
Células NK
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Summary:Abstract The role of the different arms of the Immune System in the control and elimination of tumors has been the subject of increasing interest in recent years. Here, some recent findings adding support to the role of NK cells in the elimination of spontaneous tumors in transgenic models of tumorigenesis (Guerra et al, 2008), or the role of adaptive immunity in the maintenance of chemically induced tumors as a chronic disease (Koebel et al, 2007) will be discussed within the frame of the “immunoediting” theory.
ISSN:0213-9626
DOI:10.1016/S0213-9626(08)70062-3