Matrix metalloproteinase-2 of human carotid atherosclerotic plaques promotes platelet activation. Correlation with ischaemic events

Purified active matrix metalloproteinase-2 (MMP-2) is able to promote platelet aggregation. We aimed to assess the role of MMP-2 expressed in atherosclerotic plaques in the platelet-activating potential of human carotid plaques and its correlation with ischaemic events. Carotid plaques from 81 patie...

Full description

Saved in:

Bibliographic Details
Published in:	Thrombosis and haemostasis Vol. 111; no. 6; p. 1089
Main Authors:	Lenti, Massimo, Falcinelli, Emanuela, Pompili, Marcella, de Rango, Paola, Conti, Valentina, Guglielmini, Giuseppe, Momi, Stefania, Corazzi, Teresa, Giordano, Giuseppe, Gresele, Paolo
Format:	Journal Article
Language:	English
Published:	Germany 01-06-2014
Subjects:	Brain Ischemia - blood Brain Ischemia - enzymology Brain Ischemia - etiology Carotid Artery Diseases - blood Carotid Artery Diseases - complications Carotid Artery Diseases - enzymology Enzyme Precursors - physiology Gelatinases - physiology Humans Matrix Metalloproteinase 2 - physiology Matrix Metalloproteinase Inhibitors - pharmacology Models, Cardiovascular Plaque, Atherosclerotic - blood Plaque, Atherosclerotic - complications Plaque, Atherosclerotic - enzymology Platelet Activation - drug effects Platelet Activation - physiology Platelet Aggregation - physiology Tissue Inhibitor of Metalloproteinase-2 - physiology TIA/stroke biomarker matrix metalloproteinases platelets Atherosclerotic plaques
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!