Comparison of muscle flaps and delayed secondary intention wound healing for infected lower extremity arterial grafts

• Published in: Annals of vascular surgery Vol. 8; no. 1; p. 31
• Main Authors: Calligaro, K D, Veith, F J, Sales, C M, Dougherty, M J, Savarese, R P, DeLaurentis, D A
• Format: Journal Article
• Language: English
• Published: Netherlands 01-01-1994
• Subjects: Aged; Aged, 80 and over; Arteries - surgery; Blood Vessel Prosthesis; Cost-Benefit Analysis; Debridement; Female; Follow-Up Studies; Humans; Leg - blood supply; Length of Stay; Male; Middle Aged; Prosthesis-Related Infections - economics; Prosthesis-Related Infections - surgery; Surgical Flaps; Treatment Outcome; Wound Healing
• ISSN: 0890-5096
• DOI: 10.1007/BF02133403

Selective preservation of infected arterial grafts is an alternative to graft excision. The purpose of this study was to compare the outcome and cost of treating infected lower extremity arterial grafts with either muscle flaps (MFs) or delayed secondary intention (DSI) wound healing. Between 1985 and 1991 we treated 28 graft infections by graft preservation. All grafts (19 polytetrafluoroethylene, 8 autologous vein, and 1 Dacron) were patent with intact anastomoses and showed no signs of sepsis. Wounds in 18 patients were treated by repeated, aggressive operative debridement and allowed to heal by DSI. Wounds in 10 patients were treated with MFs (4 sartorius, 3 gracilis, 1 rectus abdominis, 1 semimembranous, and 1 gastrocnemius). Costs included anesthesiologists' and surgeons' fees, operating room charges, and daily semiprivate and ICU bed charges. Four (14%) patients died from cardiac complications (1 DSI and 1 MF), sepsis (1 MF), and anastomotic hemorrhage (1 DSI). Of the 24 survivors, 4 patients treated by DSI required graft excision for nonhealing wounds (2), graft thrombosis (1), and recurrent infection (1). However, 3 of these 4 patients were not candidates for MFs because the wounds were not considered acceptable for a flap. Twenty (83%) grafts in survivors were successfully preserved after long-term follow-up (mean 26 mo). No survivors required an amputation. Twenty patients who did not require graft removal were compared for treatment by MF (n = 8) or DSI (n = 12). Two MFs (both sartorius) in survivors necrosed and a new flap was required to successfully preserve the graft.