Randomized clinical trials in breast cancer

Before the second half of this century, treatment approaches to breast cancer were radical and disfiguring. In the past four decades, however, multiple prospective randomized trials have made highly significant advances in the management of patients with this disease. These trials have established,...

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Bibliographic Details
Published in:	Surgical oncology clinics of North America Vol. 11; no. 1; p. 53
Main Authors:	Klauber-Demore, Nancy, Boolbol, Susan K, Derossis, Anna M, Ruo, Leyo, Bernik, Stephanie F, Borgen, Patrick I
Format:	Journal Article
Language:	English
Published:	United States 01-01-2002
Subjects:	Breast Neoplasms - therapy Evidence-Based Medicine Female Humans Medical Oncology Meta-Analysis as Topic Prospective Studies Randomized Controlled Trials as Topic
Online Access:	Get more information
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Summary:	Before the second half of this century, treatment approaches to breast cancer were radical and disfiguring. In the past four decades, however, multiple prospective randomized trials have made highly significant advances in the management of patients with this disease. These trials have established, in select patients, breast conservation therapy as a primary therapeutic procedure, and radiation therapy as a means to improve local control and survival. This article provides an overview of some of these trials.
ISSN:	1055-3207
DOI:	10.1016/S1055-3207(03)00075-9