Comparison of pancreatic enzyme abnormalities and protease-activated receptor-2-positive eosinophils in the duodenum of patients with functional dyspepsia-irritable bowel syndrome overlap with functional dyspepsia alone in Asian populations

Some patients with functional gastrointestinal disorders exhibit pancreatic dysfunctions and pancreatic enzyme abnormalities. Thus, we aimed to clarify whether significant differences in clinical characteristics, prevalence of pancreatic enzyme abnormalities, duodenal inflammation, and protease-acti...

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Bibliographic Details
Published in:	Journal of gastroenterology and hepatology Vol. 38; no. 10; pp. 1778 - 1786
Main Authors:	Futagami, Seiji, Kessoku, Takaomi, Kasai, Yuki, Higurashi, Takuma, Nakajima, Atsushi, Agawa, Shuhei, Yamawaki, Hiroshi, Nakamura, Ken, Habiro, Mayu, Kawawa, Rie, Ueki, Nobue, Higashida, Sakura, Watanabe, Yoshiyuki, Yamato, Hiroshi, Yamamoto, Takatsugu, Takasaki, Yusuke, Ito, Koichi, Hojo, Mariko, Isayama, Hiroyuki, Motoda, Norio, Ohashi, Ryuji, Siah, Kewin Tien Ho, Ng, Carissa Kahmun, Gwee, Kok-Ann
Format:	Journal Article
Language:	English
Published:	Australia Wiley Subscription Services, Inc 01-10-2023
Subjects:	Duodenum Dyspepsia Elastase Enzymes Eotaxin Gastrointestinal diseases Hypersensitivity Intestine Irritable bowel syndrome Leukocytes (eosinophilic) mRNA Pancreas Phospholipase A2 Small intestine Trypsin protease activated receptor 2 (PAR2) degranulated eosinophil irritable bowel syndrome (IBS) functional dyspepsia (FD) FD-IBS overlap
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