Eosinophil Regulatory Activity in Models of Virus-Induced Inflammation

Eosinophil Regulatory Activity in Models of Virus-Induced Inflammation

Using an in vitro co-culture system, purified human peripheral blood EOS were incubated with primary human PBMCs or monocytes and stimulated by poly I: The presence of EOS alters in vitro cytokine expression of PBMCs, monocytes and ECs. [...]EOS may affect host response to viral infection in asthma...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology Vol. 123; no. 2; p. S252
Main Authors: Kelly, J.T, Fox, K.E, Lucey, E.H, Mathur, S.K
Format: Journal Article
Language:English
Published: St. Louis Mosby, Inc 01-02-2009
Elsevier Limited
Subjects:
Allergy and Immunology
Asthma
Cytokines
Medical research
Viral infections
Online Access:Get full text
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Description
Summary:Using an in vitro co-culture system, purified human peripheral blood EOS were incubated with primary human PBMCs or monocytes and stimulated by poly I: The presence of EOS alters in vitro cytokine expression of PBMCs, monocytes and ECs. [...]EOS may affect host response to viral infection in asthma by altering cytokine production of inflammatory cells as well as epithelial cells.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2008.12.973