Differential genomics and transcriptomics between tyrosine kinase inhibitor-sensitive and -resistant BCR-ABL-dependent chronic myeloid leukemia

Previously, it has been stated that the BCR-ABL fusion-protein is sufficient to induce Chronic Myeloid Leukemia (CML), but additional genomic-changes are required for disease progression. Hence, we profiled control and tyrosine kinase inhibitors (TKI) alone or in combination with other drug-treated...

Full description

Bibliographic Details

Published in:	Oncotarget Vol. 9; no. 54; pp. 30385 - 30418
Main Authors:	Singh, Neetu, Tripathi, Anil Kumar, Sahu, Dinesh Kumar, Mishra, Archana, Linan, Margaret, Argente, Bianca, Varkey, Julia, Parida, Niranjan, Chowdhry, Rebecca, Shyam, Hari, Alam, Nawazish, Dixit, Shivani, Shankar, Pratap, Mishra, Abhishek, Agarwal, Avinash, Yoo, Chris, Bhatt, Madan Lal Brahma, Kant, Ravi
Format:	Journal Article
Language:	English
Published:	United States Impact Journals LLC 13-07-2018
Subjects:	Research Paper tyrosine kinase inhibitors human-transcriptome array 2.0 chronic myeloid leukemia axiom biobank array molecular-inversion-probe based array
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!