Kinetics of antagonism at histamine-H1 receptors in isolated rabbit arteries

Kinetics of antagonist-induced decrease of histamine-H1 receptor-mediated steady-state responses in isolated rabbit arteries were studied in the presence of histamine-H2 receptor antagonist famotidine. Data were fitted using a model which describes competition kinetics at the receptor level. Estimat...

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Bibliographic Details
Published in:	Naunyn-Schmiedeberg's archives of pharmacology Vol. 341; no. 4; pp. 316 - 323
Main Authors:	ONGUN ONARAN, H, ARDA BOÊKESOY, T
Format:	Journal Article
Language:	English
Published:	Heidelberg Springer 01-04-1990 Berlin New York, NY
Subjects:	Animals Antazoline - pharmacology Arteries - drug effects Biological and medical sciences Brompheniramine - pharmacology Female Histamine - pharmacology Histamine and antagonists. Allergy Histamine H1 Antagonists - pharmacology In Vitro Techniques Kinetics Male Medical sciences Muscle, Smooth, Vascular - drug effects Pharmacology. Drug treatments Pyrilamine - pharmacology Rabbits Statistical analysis Rabbit Lagomorpha Antihistaminic In vitro Artery H1 receptor Histamine Vertebrata Biological fixation Mammalia Animal Blood vessel Kinetics
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