Orthotopic liver transplantation with hepatopancreato- duodenectomy for hilar cholangiocarcinoma

• Published in: Chinese medical journal Vol. 120; no. 3; pp. 251 - 253
• Main Authors: HE, Xiao-shun, ZHANG, Shao, ZHU, Xiao-feng, WANG, Dong-ping, MA, Yi, WANG, Guo-dong, JU, Wei-qiang, WU, Lin-wei, HUANG, Jie-fu
• Format: Journal Article
• Language: English
• Published: 05-02-2007
• Subjects: 同位移植; 肝移植; 肝胰十二指肠切除术; 肝门胆管癌
• ISSN: 0366-6999; 2542-5641
• DOI: 10.1097/00029330-200702010-00017

Although the surgical treatment for hilar cholangiocarcinoma represents the only potentially curative option, local excision and major hepatectomyl have failed to produce a favorable survival figure over the last decade. This is partly due to local tumor recurrences within the resection margin, perineural sheaths infiltration, and the regional lymph nodes metastasis after the surgery. Recently; an extended bile duct resection combined with total hepatectomy, pancreatoduodenectomy, and orthotopic fiver transplantation （HPLTx） was proposed to eradicate the entire biliary tract without cutting off the hepatoduodenal ligament. The results demonstrated an increased rate of curative （Ro） resections from 29% to 93% by HPLTx, and a favour＇able 5-year survival rate. We report here on a patient with advanced fiver disease associated with hilar cholangiocareinoma, who was treated successfully by HPLTx.