Eosinophilic cholecystitis: a retrospective study spanning a fourteen-year period
Eosinophilic cholecystitis is a rare entity that was first described in 1949 and is clinically indistinguishable from calculous cholecystitis. Histologically, there is transmural inflammatory infiltration of the gallbladder wall, more than 90% of which is composed of eosinophils. The aim of the pres...
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Published in: | Revista de Gastroenterología de México (English Edition) Vol. 83; no. 4; pp. 405 - 409 |
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Main Authors: | , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
Masson Doyma México S.A
01-10-2018
Elsevier |
Subjects: | |
Online Access: | Get full text |
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Summary: | Eosinophilic cholecystitis is a rare entity that was first described in 1949 and is clinically indistinguishable from calculous cholecystitis. Histologically, there is transmural inflammatory infiltration of the gallbladder wall, more than 90% of which is composed of eosinophils. The aim of the present article was to review the prevalence of eosinophilic cholecystitis and analyze the clinical and surgical characteristics of patients diagnosed with the disease that were operated on at our hospital.
A retrospective study was conducted on patients that underwent cholecystectomy and whose postoperative histopathologic diagnosis was eosinophilic cholecystitis, within the time frame of January 2000 and August 2014. The demographic, clinical, paraclinical, surgical, and histopathologic variables were described.
Over a period of 14 years, a total of 7,494 patients underwent cholecystectomy. Of those patients, 12 had a postoperative histologic diagnosis of eosinophilic cholecystitis. Mean patient age for disease presentation was 39 years (±11 years), and female sex was predominant, with 7 cases. All the patients had concomitant gallstones and 10 patients presented with acute cholecystitis that required urgent cholecystectomy. All the cases were considered idiopathic. We found a prevalence of 0.16%, corresponding to 1 case for every 625 cholecystectomies performed at our hospital.
We found a low prevalence of eosinophilic cholecystitis (0.16%) in our study population. The clinical manifestations were similar to those of calculous cholecystitis. Cholecystectomy is adequate treatment in patients with idiopathic disease.
La colecistitis eosinofílica es una entidad rara que se describió por primera vez en 1949 y es clínicamente indistinguible de la colecistitis litiásica. Histológicamente, hay infiltración inflamatoria transmural de la pared de la vesícula biliar con más del 90% de eosinófilos. El objetivo del presente trabajo es revisar la prevalencia y analizar las características clínico-quirúrgicas de los pacientes con diagnóstico de colecistitis eosinofílica operados en nuestro hospital.
Se trata de un estudio retrospectivo (de enero del 2000 a agosto del 2014) en el que se incluyeron pacientes postoperados de colecistectomía con diagnóstico histopatológico de colecistitis eosinofílica. Se describen variables demográficas, clínicas, paraclínicas, quirúrgicas e histopatológicas.
Se encontraron un total de 7,494 pacientes postoperados de colecistectomía en un período de 14 años, de los cuales 12 pacientes tuvieron el diagnóstico postoperatorio histopatológico de colecistitis eosinofílica. La edad media de presentación fue de 39 años (±11 años), y predominó el sexo femenino con 7 casos. Todos los pacientes tenían colelitiasis concomitante y 10 de ellos se presentaron con colecistitis aguda, que requirió colecistectomía de urgencia. Todos los casos se consideraron idiopáticos. Encontramos una prevalencia del 0.16%, que corresponde a un caso por cada 625 colecistectomías llevadas a cabo en nuestra institución.
Encontramos una prevalencia baja de colecistitis eosinofílica (0.16%) en nuestra población de estudio. Las manifestaciones clínicas se asemejan a las que se presentan en colecistitis litiásica. La colecistectomía es el tratamiento adecuado en pacientes con esta entidad de etiología idiopática. |
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ISSN: | 2255-534X 2255-534X |
DOI: | 10.1016/j.rgmxen.2018.09.002 |