High prevalence of TSHR/Gsα mutation-negative clonal hot thyroid nodules (HNs) in a Turkish cohort

Whereas the majority of hot thyroid nodules are caused by somatic TSH-receptor mutations, the percentage of TSH-receptor mutation negative clonal hot nodules (HN) and thus the percentage of hot nodules likely caused by other somatic mutations are still debated. This is especially the case for toxic...

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Bibliographic Details
Published in:	Hormone and metabolic research Vol. 43; no. 8; p. 562
Main Authors:	Sancak, S, Jaeschke, H, Eren, F, Tarcin, O, Ozlem, T, Guellueoglu, B, Sen, L S, Sever, Z, Gozu, H I, Bircan, R, Akalin, S, Paschke, R, Eszlinger, M
Format:	Journal Article
Language:	English
Published:	Germany 01-07-2011
Subjects:	Adult Aged Animals Cercopithecus aethiops Clone Cells Cohort Studies COS Cells Female Goiter, Nodular - genetics GTP-Binding Protein alpha Subunits, Gs - genetics Humans Linear Models Male Middle Aged Mutation - genetics Prevalence Receptors, Thyrotropin - genetics Thyroid Nodule - epidemiology Thyroid Nodule - genetics Turkey - epidemiology Young Adult Turkey
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