Recent trends in the nitrergic nervous system
The late 20th century witnessed the novel discovery of "Nitrergic" or "Nitroxidergic" innervation of the vascular smooth muscles, their role as a vasodilator in cerebral, ocular and penile vasculature, as well as their reciprocal action to adrenergic vasoconstriction. The identif...
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| Published in: | Indian journal of pharmacology Vol. 37; no. 2; p. 69 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
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Pondicherry
Medknow Publications and Media Pvt. Ltd
01-03-2005
Medknow Publications & Media Pvt. Ltd |
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| Abstract | The late 20th century witnessed the novel discovery of "Nitrergic" or "Nitroxidergic" innervation of the vascular smooth muscles, their role as a vasodilator in cerebral, ocular and penile vasculature, as well as their reciprocal action to adrenergic vasoconstriction. The identification of this nerve as a postganglionic parasympathetic nerve, the discovery of autonomic efferent nerves where Nitric oxide (NO) is the neurotransmitter (NTM) to blood vessels, its physiological role in the control of smooth muscle tone, and the pharmacological implications of NO have been reviewed. This will aid an in-depth analysis of vascular dysfunctions and the development of strategic pharmacotherapeutic interventions with time. |
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| AbstractList | The late 20th century witnessed the novel discovery of "Nitrergic" or "Nitroxidergic" innervation of the vascular smooth muscles, their role as a vasodilator in cerebral, ocular and penile vasculature, as well as their reciprocal action to adrenergic vasoconstriction. The identification of this nerve as a postganglionic parasympathetic nerve, the discovery of autonomic efferent nerves where Nitric oxide (NO) is the neurotransmitter (NTM) to blood vessels, its physiological role in the control of smooth muscle tone, and the pharmacological implications of NO have been reviewed. This will aid an in-depth analysis of vascular dysfunctions and the development of strategic pharmacotherapeutic interventions with time. |
| Audience | Academic |
| Author | Roy, P Naidu, M Rani, P. Usha Ramana, G. Venkat |
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| Copyright | COPYRIGHT 2005 Medknow Publications and Media Pvt. Ltd. Copyright Medknow Publications Mar/Apr 2005 |
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| DOI | 10.4103/0253-7613.15105 |
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| Title | Recent trends in the nitrergic nervous system |
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