Effectiveness of antimicrobial photodynamic therapy using a 660 nm laser and methyline blue dye for inactivating Staphylococcus aureus biofilms in compact and cancellous bones: An in vitro study

Highlights • We evaluated the antimicrobial photodynamic therapy to inactivate S. aureus biofilms. • We used an in vitro model to form biofilms on bone tissues. • The experimental treatments showed a significant reduction compared with the control group. • Compact specimens showed the greatest reduc...

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Bibliographic Details
Published in:	Photodiagnosis and photodynamic therapy Vol. 12; no. 2; pp. 276 - 281
Main Authors:	Rosa, Luciano Pereira, PhD, Silva, Francine Cristina da, Nader, Sumaia Alves, Meira, Giselle Andrade, Viana, Magda Souza
Format:	Journal Article
Language:	English
Published:	Netherlands 01-06-2015
Subjects:	Animals Anti-Infective Agents - therapeutic use Biofilms - drug effects Bone and Bones - drug effects Bone and Bones - microbiology Cattle Hematology, Oncology and Palliative Medicine Internal Medicine Lasers Methylene Blue Photochemotherapy - methods Photosensitizing Agents - therapeutic use Staphylococcus aureus - drug effects Biofilm Photodynamic therapy Microorganism Staphylococcus aureus Methylene blue
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Summary:	Highlights • We evaluated the antimicrobial photodynamic therapy to inactivate S. aureus biofilms. • We used an in vitro model to form biofilms on bone tissues. • The experimental treatments showed a significant reduction compared with the control group. • Compact specimens showed the greatest reduction in biofilms compared with cancellous specimens.
ISSN:	1572-1000 1873-1597
DOI:	10.1016/j.pdpdt.2015.01.001