Development and synthesis of a novel salen-type ligand based on phenylalanine for Mizoroki-Heck, and S -arylation cross-coupling reactions

In this article, we introduced a novel salen-type ligand precursor and applied it in the Pd-catalyzed Mizoroki-Heck and Cu-catalyzed -arylation cross-coupling reactions. For the preparation of this structure, ( )-phenyl alanine was employed as a starting material. These ligand precursor and related...

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Bibliographic Details
Published in:	Natural product research pp. 1 - 9
Main Authors:	Salmani Nezhad, Bahnood, Habibi, Azizollah, Takallou, Ahmad, Badali, Elham, Kumar Avula, Satya, Al-Harrasi, Ahmed
Format:	Journal Article
Language:	English
Published:	England 23-03-2024
Subjects:	Mizoroki-Heck reaction cross-coupling reaction S-arylation substituted carbamodithioate Salen-type ligand
Online Access:	Get full text
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Summary:	In this article, we introduced a novel salen-type ligand precursor and applied it in the Pd-catalyzed Mizoroki-Heck and Cu-catalyzed -arylation cross-coupling reactions. For the preparation of this structure, ( )-phenyl alanine was employed as a starting material. These ligand precursor and related catalytic system can be readily synthesised. Various aryl halides (-I, -Br) and alkenes were applied successfully in this protocol to give the corresponding Mizoroki-Heck cross-coupling and -arylated products in high to excellent yields.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1478-6419 1478-6427
DOI:	10.1080/14786419.2024.2326853