Elongated particulate burden in an individual who died of mesothelioma and had an occupational history as a talc "mucker"

Tissue from a 77-year-old man diagnosed with mesothelioma was referred with a request for identification of the presence of fibrous structures in tissue samples. The individual's work history including working as a "mucker" at a specific "industrial" talc mine. Ferruginous b...

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Bibliographic Details
Published in:Inhalation toxicology Vol. 36; no. 3; pp. 205 - 216
Main Authors: Dodson, Ronald F, Moline, Jacqueline, Salinas, Carlos D, Poye, Lee W
Format: Journal Article
Language:English
Published: England 15-03-2024
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Summary:Tissue from a 77-year-old man diagnosed with mesothelioma was referred with a request for identification of the presence of fibrous structures in tissue samples. The individual's work history including working as a "mucker" at a specific "industrial" talc mine. Ferruginous bodies in the tissue digests as well as asbestos fibers were found. A bulk sample of a talc containing product from that mine was also analyzed. The correlation between the unique asbestos mineral/fibrous content of the talc to which he was exposed and findings of the same type of asbestos found in his lung is discussed. The type of asbestos found (tremolite) is a "non-commercial" type of asbestos that has been identified in some talc deposits. Tremolite, like all forms of asbestos is a causative agent for mesothelioma-the disease from which this individual suffered.
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ISSN:0895-8378
1091-7691
DOI:10.1080/08958378.2024.2329935